Medical

Creatinine Clearance Calculator

Estimate kidney function for drug dose adjustment. Cockcroft-Gault formula with KDIGO CKD staging.

Sex
Serum creatinine unit
Adult formula — Cockcroft-Gault is validated for ≥18.
Actual body weight. For BMI >30, use adjusted body weight below.
From the lab report.
Estimate only. Creatinine clearance overestimates true GFR by about 10–20% (StatPearls). Use clinical judgement.

Creatinine clearance

mL/min

G2 — Mildly decreased

KDIGO GFR category (guide)G2

KDIGO counts G1 and G2 as chronic kidney disease only when there are other signs of kidney damage, such as protein or blood in the urine.

Formula used(140 − 65) × 70 × 1 / (72 × 1.2)
Serum Cr (mg/dL)1.2
Weight used70 kg

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Frequently asked questions

Both are in use. StatPearls notes that for estimating GFR, CKD-EPI has mainly replaced Cockcroft-Gault and MDRD, and KDIGO 2024 says validated creatinine-based eGFR equations suit drug dosing for most people. Australian Prescriber notes there is still debate over which is better for dosing. Use the formula that the drug's dosing reference uses.

Cockcroft and Gault's 1976 paper reported values 15% lower in women, so the result is multiplied by 0.85. StatPearls describes it as a correction for the lower creatinine clearance in women.

Australian Prescriber's 2019 review says that with a BMI over 30 kg/m², or weight over 120 kg, Cockcroft-Gault on actual body weight overestimates GFR, and recommends adjusted ideal body weight: IBW + 0.4 × (actual weight − IBW). The calculator switches to that weight when you tick the box, enter a height and the BMI is over 30.

The same review rates Cockcroft-Gault with actual body weight as acceptable when BMI is under 18.5 or weight is under 60 kg. Where a creatinine-based estimate may be unreliable, KDIGO 2024 suggests an equation that adds cystatin C, or a measured GFR.

StatPearls notes that creatinine is also secreted by the kidney tubules, so creatinine clearance overestimates true GFR by about 10% to 20%. A figure such as 73.4 mL/min suggests more precision than the estimate has, so the result is shown to the nearest whole number.

No. The 1976 formula was derived from patients aged 18 to 92, and the calculator stops below 18. StatPearls says GFR in children is usually estimated with the CKiD (bedside Schwartz) equation, which uses serum creatinine and height.

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Source: Cockcroft & Gault 1976 (Nephron 16:31); KDIGO 2024 CKD guideline; StatPearls · Last verified 2026-11. StatPearls: Creatinine Clearance. This tool provides estimates only and is not legal, tax or financial advice. Always verify your specific situation with the relevant UAE authority or a licensed advisor before taking action.